Depressive disorder can affect anyone. It may present with feelings of intense sadness or hopelessness, or as a loss of interest or pleasure in activities. People with depression can experience feelings of guilt, unworthiness, or low self-esteem, and they may start avoiding being around people. Depression is a common but serious disorder — one that typically requires some form of treatment to manage. The good news is that even the most severe cases of depression are treatable. Counseling will help explore those options in addition to helping address symptoms.